best episodes of Hamilton's Pharmacopeia poster

Join an incredible journey through the history, chemistry and societal impacts of the world’s most extraordinary drugs.

3 Seasons
20 Episodes
Ended
Documentary
Cast & Characters
episode image Synthetic Toad Venom Machine
9.2/10 (47 votes)

#1 Synthetic Toad Venom Machine

S3:E1

Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

episode image The Psychedelic Toad
9.1/10 (80 votes)

#2 The Psychedelic Toad

S2:E1

Hamilton embarks on a quest to answer the most important question in ethnoherpetological history and along the way, he finds the power of love.

episode image A Clandestine Chemist's Tale
9.0/10 (57 votes)

#3 A Clandestine Chemist's Tale

S2:E6

Hamilton meets an unsung hero of the psychedelic underground and hears a tragic tale of MDMA synthesis and chemiluminescence.

episode image The Lazy Lizard School of Hedonism
8.9/10 (63 votes)

#4 The Lazy Lizard School of Hedonism

S1:E6

We meet with famed LSD chemist Casey Hardison in the Nevada desert and embark on a roadtrip to visit the unsung hero of psychedelic history.

episode image The Story of the South African Quaalude
8.8/10 (70 votes)

#5 The Story of the South African Quaalude

S1:E1

South Africa is the last place on earth Quaaludes can still be found; Hamilton travels there to study the drug and learns of a dark history of medical experimentation.

episode image Peyote: The Divine Messenger
8.8/10 (57 votes)

#6 Peyote: The Divine Messenger

S2:E2

From the greenhouses of Thai cactophiles to the Tamaulipan thornscrub, Hamilton traces the history of peyote with the help of a Native American peyotist.

episode image A Fungal Fairy Tale
8.8/10 (46 votes)

#7 A Fungal Fairy Tale

S2:E7

Hamilton ascends the Carpathian Mountains, microscope in hand, to learn how Europeans use Amanita muscaria, and uncovers the chemistry behind a mushroom-inspired pharmaceutical.

episode image Ketamine: Realms and Realities
8.7/10 (62 votes)

#8 Ketamine: Realms and Realities

S2:E5

Hamilton heads to India to see industrial Ketamine synthesis, and speak with therapists and luminaries in an attempt to understand the role of dissociative anesthetics in society.

episode image A Positive PCP Story
8.6/10 (58 votes)

#9 A Positive PCP Story

S1:E2

Hamilton investigates the history of PCP in the U.S., seeking input from addicts, dealers and chemists.

episode image Magic Mushrooms in Mexico
8.6/10 (61 votes)

#10 Magic Mushrooms in Mexico

S1:E4

Hamilton explores magic mushrooms with the help of shamans, clandestine growers, and ethnomycologists.

episode image The Cactus Apprentice
8.6/10 (39 votes)

#11 The Cactus Apprentice

S2:E8

Deep in the Andean highlands of Peru, Hamilton becomes the apprentice of a local shaman, learning how to use the night-blooming San Pedro cactus as a medicine.

episode image Shepherdess: The Story of Salvia Divinorium
0.0/10

#12 Shepherdess: The Story of Salvia Divinorium

S1:E3

From the heavenly cloud forests of Oaxaca to a viral video of Miley Cyrus, Hamilton investigates the inconspicuous yet extraordinary psychedelic plant Salvia divinorum.

episode image Fish N' Trips
0.0/10

#13 Fish N' Trips

S1:E5

Hamilton embarks on an aquatic adventure to Reunion Island and Madagascar to investigate ichthyoallyeinotoxism and a twisted history of hallucinogenic fish.

episode image Kratom: The Forbidden Leaf
0.0/10

#14 Kratom: The Forbidden Leaf

S2:E3

Hamilton investigates the pharmacology and traditional uses of Kratom, a Thai tree with opioid-containing leaves.

episode image Wizards of DMT
0.0/10

#15 Wizards of DMT

S2:E4

Hamilton travels across North America to study how and why DMT exists in the environment and the laboratory.

episode image A Positive Methamphetamine Story
0.0/10

#16 A Positive Methamphetamine Story

S3:E2

From X-ray crystallography to vesicular dopamine release, Hamilton travels the country visiting meth labs in order to understand the process behind a great American folk art.

episode image Xenon: the Perfect Anesthetic?
0.0/10

#17 Xenon: the Perfect Anesthetic?

S3:E3

Hamilton traces the multibillion year history of nitrous oxide on Earth and follows the strangest noble gas to the Czech Republic.

episode image Synethetic Ibogaine-Natural Tramadol
0.0/10

#18 Synethetic Ibogaine-Natural Tramadol

S3:E4

After revealing a scientific mystery around Tramadol-addicted cows in Central Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.

episode image Bufotenine: In Search of Hataj
0.0/10

#19 Bufotenine: In Search of Hataj

S3:E5

Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.

episode image Ultra LSD
0.0/10

#20 Ultra LSD

S3:E6

With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.

Cast & Chracters

character image Self

Self

Actor: Hamilton Morris

The highest rated episode of Hamilton's Pharmacopeia is "Synthetic Toad Venom Machine" (S3E1) with a rating of 9.20.

This episode received 47 votes.


The lowest rated episode is "A Positive PCP Story" (S1E2) with a rating of 8.60.

This episode received 58 votes.

The highest rated episode is "The Lazy Lizard School of Hedonism" (S1E6) with a rating of 8.90.

This episode received 63 votes.


The lowest rated episode is "A Positive PCP Story" (S1E2) with a rating of 8.60.

This episode received 58 votes.

The highest rated episode is "The Psychedelic Toad" (S2E1) with a rating of 9.10.

This episode received 80 votes.


The lowest rated episode is "The Cactus Apprentice" (S2E8) with a rating of 8.60.

This episode received 39 votes.

The highest rated episode is "Synthetic Toad Venom Machine" (S3E1) with a rating of 9.20.

This episode received 47 votes.


The lowest rated episode is "Synthetic Toad Venom Machine" (S3E1) with a rating of 9.20.

This episode received 47 votes.

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